How Is Neuromyelitis Optica Spectrum Disorder (NMOSD) Treated?

Neurological and Brain Health
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  • Acute Attacks: High-dose intravenous corticosteroids (like methylprednisolone) and sometimes plasma exchange.
  • Long-term Management: Immunosuppressive drugs like corticosteroids, azathioprine, mycophenolate mofetil, and rituximab.
  • FDA-approved Treatments: Soliris (eculizumab), Uplizna (inebilizumab-cdon), and Enspryng (satralizumab-mwge) for AQP4 antibody-positive patients.
  • Symptom Management: Medications to control spasms and manage long-term muscle stiffness.