The symptoms of leishmaniasis depend on the type of infection and can range from mild skin lesions to severe systemic illness. In cutaneous leishmaniasis, symptoms typically include skin sores or ulcers at the site of the sandfly bite, which may develop weeks to months after exposure. Mucocutaneous leishmaniasis can cause destructive lesions in the mucous membranes of the nose, mouth, and throat. Visceral leishmaniasis, also known as kala-azar, affects internal organs such as the spleen, liver, and bone marrow, leading to fever, weight loss, enlarged spleen and liver, and anemia.