Symptoms of MPDs can vary depending on the specific disorder but often include:
- Fatigue: Persistent tiredness due to anemia or other blood abnormalities.
- Headaches and Dizziness: Resulting from increased blood viscosity in polycythemia vera.
- Bleeding or Bruising Easily: Due to abnormal platelet function.
- Night Sweats and Fever: Common in myelofibrosis and other advanced MPDs.
- Splenomegaly: Enlarged spleen causing discomfort or pain in the left upper abdomen.
- Bone Pain: Especially in myelofibrosis due to bone marrow scarring.