Treatment for polycythemia vera aims to reduce blood viscosity, manage symptoms, and prevent complications:
- Phlebotomy: Regular removal of blood to decrease red blood cell mass and reduce blood thickness.
- Medications: Hydroxyurea to reduce the production of red blood cells, and aspirin to decrease the risk of blood clots.
- JAK2 Inhibitors: Such as ruxolitinib, which can help manage symptoms and reduce spleen size in patients with PV.
- Interferon-alpha: Used in some cases to control blood counts, particularly in younger patients or those who cannot tolerate other medications.
- Antihistamines: For managing itching.
- Hydration: Ensuring adequate fluid intake to help decrease blood viscosity.