The exact cause of NHL is not known, but several risk factors can increase the likelihood of developing the disease:
- Age: The risk increases with age, particularly in individuals over 60.
- Weakened Immune System: People with weakened immune systems, such as those with HIV/AIDS, autoimmune diseases, or organ transplant recipients taking immunosuppressive drugs, are at higher risk.
- Infections: Certain infections, such as Epstein-Barr virus (EBV), human T-cell leukemia/lymphoma virus (HTLV-1), and Helicobacter pylori, are associated with an increased risk of NHL.
- Exposure to Chemicals: Exposure to certain chemicals, such as pesticides and herbicides, may increase the risk.
- Genetic Factors: A family history of lymphoma can also play a role.