What Is a Cold Knife Cone Biopsy?

A cold knife cone biopsy, also known as a conization, is a surgical procedure in which a cone-shaped piece of tissue is removed from the cervix. This procedure is typically performed to diagnose and treat precancerous changes or early-stage cervical cancer. The term “cold knife” refers to the use of a scalpel or surgical knife, as opposed to a laser or electrical loop.