Why Is a Muscle Biopsy Performed?

A muscle biopsy is performed to diagnose a variety of muscular and neuromuscular conditions, such as:

  • Muscular Dystrophy: To determine the presence and type of muscular dystrophy, which is a group of genetic disorders that cause muscle weakness and degeneration.
  • Inflammatory Myopathies: Such as polymyositis or dermatomyositis, where the immune system attacks muscle tissue.
  • Metabolic Muscle Diseases: Conditions that affect the muscle’s ability to process energy, such as mitochondrial myopathy or glycogen storage diseases.
  • Infections: To detect muscle infections caused by bacteria, viruses, or parasites.
  • Other Muscle Abnormalities: To investigate unexplained muscle pain, cramps, or weakness.